The Buffalo Bills didn't just beat the San Francisco 49ers on Sunday night. They destroyed the reigning NFC champions. The 49ers started hot with a field goal on their opening drive. From there, they were outscored by a robust 35-7 margin in a game that somehow didn't

The Buffalo Bills' first snow game of the season comes in an important showdown Sunday night against the San Francisco 49ers.

The San Francisco 49ers will have to deal with some real inclement weather for the first time this season when they visit the Buffalo Bills at Highmark Stadium. Just hours before kickoff, the field and seats were covered with snow due to a bevy of snow showers that

Following a brutal 38-10 loss to the Green Bay Packers last week, things didn't get any easier for the San Francisco 49ers

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills clinched their fifth straight AFC East title with a 35-10 victory over the San Francisco 49ers on a snowy Sunday night.

The San Francisco 49ers' losses to the Green Bay Packers and Buffalo Bills mark the worst two-game stretch by a defending conference champion since the 1970 merger.

The Buffalo Bills have activated Matt Milano from injured reserve, putting the starting linebacker in position to play Sunday night against the San Francisco 49ers