San Francisco 49ers QB Brock Purdy (shoulder) is questionable to play in Sunday night's showdown against the Buffalo Bills, head coach Kyle Shanahan announced Friday.

There are no teams on bye around the NFL in Week 13, which means we'll be treated to a packed slate of Sunday games even after seeing four games played on Thursday and Friday. Amo

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an injury to his throwing shoulder.

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in the fold?

All six of the NFL teams playing on Thanksgiving will be without critical players. The Chicago Bears will be without center Ryan Bates (concussion). The Detroit Lions will be without cornerback Carlton Davis III (knee/thumb) and left tackle Taylor Decker (knee).

San Francisco quarterback Brock Purdy took part in some light throwing after missing his first career game because of an injury and the 49ers are hoping he can return this week.

San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there is growing concern about the long-term status of left tackle Trent Williams.