The Buffalo Bills proved snow can't stop them, which we've seen time and again in Western New York (hey, why are they ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as "potentially" ...

Watch all of Buffalo Bills running back James Cook's best plays from his 120-yard game in an AFC East-clinching win over the ...

The Buffalo Bills are used to hosting high-stakes games in the snow. So, it might not be a surprise that they easily defeated ...

San Francisco star running back Christian McCaffrey exited the 49ers Sunday Night Football game against the Bills with a knee ...

The Bills and 49ers play Sunday, Dec. 1 at 8:20 p.m. at Highmark Stadium in Orchard Park. The game will be broadcast on local ...

San Francisco 49ers star running back Christian McCaffrey departed Sunday night's snow game against the Buffalo Bills early ...

San Francisco 49ers quarterback Brock Purdy official game status revealed for Week 13 primetime matchup against the Buffalo ...

San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...

We're live with the Week 13 edition of "Sunday Night Football" as the Buffalo Bills play host to the San Francisco 49ers to ...

The worst fears for the San Francisco 49ers and star Christian McCaffrey may have been realized, as the star running back ...

NFL Week 13 closes with Sunday Night Football as the San Francisco 49ers visit Highmark Stadium and the Buffalo Bills. Time ...