Isaac Guerendo was initially uncertain for Thursday night, but the rookie looks like he might give it a go. Here's the latest on his status.

It may look sunny and dry around the Bay Area, but come Wednesday night, rain will make its return. It will be a Level 1 ...

We open up week 15 in the NFL with one of the most important NFC West matchups this season! The Los Angeles Rams travel to ...

In a rematch of a wild Week 3 game at SoFi Stadium, the Los Angeles Rams and San Francisco 49ers will renew their rivalry tonight at Levi’s Stadium in Santa Clara. It’s a potential season-altering ...

My only concern is that we might see some rain tonight that could cause some disruptions. Still, I feel comfortable locking in a Same Game Parlay as my FanDuel Best Bet for Thursday Night Football.

San Francisco 49ers rookie running back Isaac Guerendo is dealing with a foot injury and is listed as questionable for Week 15 against the Los Angeles Rams on T ...

Six-time Super Bowl-winning head coach Bill Belichick has agree to a five-year deal to become the next coach at North ...

The Niners face an uphill battle to feature in the postseason but a Thursday Night Football win over the Rams will keep their ...

You can watch Thursday Night Football: Rams vs. 49ers at 8:20 p.m. ET/5:20 p.m. PT on Amazon Prime Video. This is it, my ...

The San Francisco 49ers hosting the Los Angeles Rams, a soft three-point favorite for San Francisco. The over-under, it has ...

With just four games left in the NFL regular season, there's a lot on the line for teams, with playoff berths and conference seed standings on the line.

Our PennLive betting experts are creating the best single game parlay bet for the Rams vs. 49ers on Thursday Night Football ...