Kyle Shanahan's team is now on a three-game losing streak, two games out of first place with only five games left to play, ...

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Hiker who helped search for missing hiker Wendy Rose reacts to hunter's discovery of body in woods ...

Dec 1, 2024; Orchard Park, New York, USA; San Francisco 49ers quarterback Brock Purdy (13) after the game against the Buffalo ...

But now it is back to the drawing board, not only for McCaffrey, but the 49ers at large. His injury, of course, is just one ...

Before the 2024 NFL season, Sunday night's Week 13 matchup between the Buffalo Bills and San Francisco 49ers might've been ...

San Francisco 49ers quarterback Brock Purdy is active for the team's Week 13 matchup versus the Buffalo Bills.

Quarterback Brock Purdy, inactive for the Week 12 loss to the Green Bay Packers last week, is expected to play head coach ...

Our NFL experts share their three favorite bets plus a special same-game parlay ahead of 49ers vs Bills on SNF on Sunday, ...

When Brock Purdy started looking visibly uncomfortable during the fourth quarter of his Week 11 showdown against the Seattle ...

Surgery could be on the horizon for Trevor Lawrence, but the Jacksonville Jaguars quarterback is expected to play on Sunday ...

Brock Purdy will make his return from a shoulder injury this Sunday when the 49ers face the Buffalo Bills. On Friday, Purdy spoke to the media for the first tim ...