Dive into the San Francisco 49ers vs. Buffalo Bills showdown with a look at odds, predictions, and the best betting options.

San Francisco 49ers vs Buffalo Bills showdown with essential stats, lineup predictions and injury updates you won’t want to ...

San Francisco 49ers quarterback Brock Purdy is expected to return to the field on Sunday against the Buffalo Bills after ...

With the Miami Dolphins taking a 30-17 loss to the Green Bay Packers on Thursday night, the Buffalo Bills can wrap up the AFC East for a fifth straight season o ...

Running back Christian McCaffrey says the San Francisco 49ers are "hungry" to make a playoff push even with the defending NFC ...

The Buffalo Bills have the chance to make team history on "Sunday Night Football" against the San Francisco 49ers.

Ravens quarterback Lamar Jackson has owned the NFC. But his 23-1 mastery will face a significant test from the Philadelphia ...

Cold weather remains the Miami Dolphins' kryptonite, as their three-game winning streak came to an end on Thanksgiving night ...

T he Buffalo Bills are coming off their bye week and getting set for the final six-game stretch of the season, beginning at ...

The Buffalo Bills (9-2) bring a six-game winning streak into a matchup with the San Francisco 49ers (5-6) on Sunday, December 1, ...

Lindsey Stirling's halftime show at the Packers vs. Dolphins game was not broadcast in full on NBC. The network faced ...