In the USA, children with sickle cell disease increasingly survive into adulthood, leading to an expanding population of ...

Advances in genetic cell modifications are performed routinely in research laboratories, but clinical translation requires ...

In 2021, alcohol-related liver cirrhosis accounted for about a quarter of the 46·4 million disability-adjusted life-years (DALYs) lost from liver disease globally, making alcohol a leading cause of ...

The past 10 years have seen an expansion in treatment possibilities for people with haemophilia, driven by the need for better protection against bleeding episodes, more efficient prevention of joint ...

Therein lies one of the most pragmatic reasons to address health inequity—inaction is financially unsustainable. However, ...

In October, the UK NHS Blood and Transplant launched a campaign encouraging people to register as a stem cell donor, stating ...

Margareth Dalcolmo has spent decades treating and researching respiratory infectious diseases, most notably tuberculosis. Yet ...

Despite substantial scientific advances, diagnosis and prognosis after paediatric traumatic brain injury (TBI) remains ...

Sudden cardiac arrest and death occur among competitive and recreational athletes across the entire spectrum of age, sex, and ...

The SELECTION study1 showed that the JAK 1 inhibitor filgotinib is safe and efficacious in ulcerative colitis. Based on positive results of the phase 2 FITZROY study2 in Crohn's disease, it was ...

This Series on Cancer Care in the South Asian Association for Regional Cooperation (SAARC) countries comprises four papers and a Reportage in The Lancet Oncology. The first two papers focus on cancer ...

In 1842, Friedrich Engels walked the streets of Manchester in the UK, noting its crowded tenements and sunless, smoke-filled ...