The San Francisco 49ers hosted a fan-focused event with the 49ers Pride Fan Group and PLUS (LGBTQ+) ERG to discuss being out ...

Watch highlights from the Week 13 matchup between the San Francisco 49ers and the Buffalo Bills during the 2024 NFL season.

San Francisco 49ers rookie running back Isaac Guerendo's 15-yard rushing score gives the 49ers their first touchdown of their ...

Temperatures reached the 20s Sunday night as snow fell throughout Buffalo’s Week 13 home game against San Francisco. For the ...

The weather outside was frightful at Highmark Stadium in Orchard Park, New York on Sunday night, but the way the San ...

The San Francisco 49ers and Green Bay Packers play on Sunday, Nov. 24 at Lambeau Field in a game on the NFL Week 12 schedule. Which team will win the NFL Week 12 game? The Packers are a 2.5-point ...

The oddsmakers are starting to lose confidence in the 49ers. For the first time since last year, the 49ers are underdogs for their upcoming game. The Packers are favored to beat them by 1.5 points.

The San Francisco 49ers rewarded cornerback Deommodore Lenoir, a key member of its secondary, with a five-year, $92 million extension, league sources said. The move comes amid another solid year ...

San Francisco 49ers quarterback Brock Purdy has high praise for rookie wide receiver Ricky Pearsall. "He's the toughest guy I know ... From getting shot in the chest to scoring an NFL touchdown a ...

How will the San Francisco 49ers replenish their defense in the years to come? For much of the Kyle Shanahan/John Lynch era, the 49ers have been spoiled when it comes to defensive talent.

How many more field goals can Jake Moody miss before the 49ers cut him? Moody missed a whopping three field goals Sunday during the 49ers' 23-20 win over the Tampa Bay Buccaneers. He was the main ...