In a rematch of a wild Week 3 game at SoFi Stadium, the Los Angeles Rams and San Francisco 49ers will renew their rivalry tonight at Levi’s Stadium in Santa Clara. It’s a potential season-altering ...

San Francisco 49ers rookie running back Isaac Guerendo is dealing with a foot injury and is listed as questionable for Week 15 against the Los Angeles Rams on T ...

Six-time Super Bowl-winning head coach Bill Belichick has agree to a five-year deal to become the next coach at North ...

You can watch Thursday Night Football: Rams vs. 49ers at 8:20 p.m. ET/5:20 p.m. PT on Amazon Prime Video. This is it, my ...

The San Francisco 49ers hosting the Los Angeles Rams, a soft three-point favorite for San Francisco. The over-under, it has ...

Our PennLive betting experts are creating the best single game parlay bet for the Rams vs. 49ers on Thursday Night Football ...

San Francisco will potentially be short-handed in its attempt to match LA’s offense, as Isaac Guerendo became just the latest ...

According to ESPN's Adam Schefter, San Francisco 49ers rookie running back Isaac Guerendo is expected to suit up for Thursday ...

Jayden Daniels and Caleb Williams are among UPI senior sports writer Alex Butler's five must-start fantasy football ...

SportsLine's model simulated the San Francisco 49ers vs. Los Angeles Rams on Thursday Night Football 10,000 times and ...

Join Packers Head Coach Matt LaFleur and analyst Larry McCarren as they discuss the Packers' Week 14 loss to the Lions and preview the Week 15 showdown in Seattle. This week's guest is Tucker Kraft.

Los Angeles Rams tight end Tyler Higbee is listed as out for Week 15 against the San Francisco 49ers as he recovers from an ACL injury last season. The veteran ...