San Francisco 49ers quarterback Brock Purdy is expected to play Sunday night against the Buffalo Bills, according to ESPN's ...

Although there aren't any teams on bye in Week 13, we already have four games in the books heading into Sunday thanks to the ...

Check out who's in and who's out for Week 13. Plus weather reports, last-minute free agency options, and Jake Ciely's fantasy ...

Kirk Cousins threw four interceptions and tossed the Atlanta Falcons’ playoff plans into disarray. Brock Purdy couldn’t ...

San Francisco 49ers quarterback Brock Purdy official game status revealed for Week 13 primetime matchup against the Buffalo ...

The ailing 49ers will have their starting quarterback under center Sunday. Brock Purdy, who missed the first start of his ...

The 49ers take on the Bills on "Sunday Night Football" in Week 13. Here's the latest on if QB Brock Purdy will be available ...

San Francisco 49ers quarterback Brock Purdy missed the team's loss to the Green Bay Packers in Week 12 with a shoulder injury ...

The situation for the San Francisco 49ers is so dire that Brock Purdy had to send a clear and forceful message to his ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

Week 13 of the NFL season brought snowstorms, interceptions, and some truly lackluster performances from several high-profile ...

The 49ers' other inactives are defensive linemen Nick Bosa (hip, oblique) and Jordan Elliott (concussion), cornerback ...