The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

The weather outside was frightful at Highmark Stadium in Orchard Park, New York on Sunday night, but the way the San ...

Officials in upstate New York counties have declared a state of emergency as they prepare for a major snowstorm that has ...

The Buffalo Bills dominated the San Francisco 49ers on Sunday night, winning 35-10 in Highmark Stadium in Orchard Park, N.Y.

One week after a 38-10 road loss to the Green Bay Packers that stood out as one of their ugliest defeats in years, the San Francisco 49ers put on a performance against the Buffalo Bills at Highmark ...

The 49ers were absolutely shellacked Sunday for a second straight week as the Buffalo Bills beat them 35-10 on national ...

The Buffalo Bills embrace the elements, possibly more than any other team in the NFL. Sure, the Packers and Steelers turn out ...

Follow along for updates throughout the game as the Buffalo Bills take on the San Francisco 49ers at snowy Highmark Stadium.

Lake-effect snow blanketed swaths of the U.S. as Thanksgiving travelers journeyed home this holiday weekend, with more snow ...

The Bills went down 3-0 early against the 49ers thanks to a field goal from kicker Jake Moody in a winter wonderland in ...

San Francisco 49ers star running back Christian McCaffrey receives huge injury update following his exit from the game due to ...

Hundreds of snow shovelers showed up at Highmark Stadium in Orchard Park, New York, to clear the two-feet of snow that has ...